For the 1999 model year, Ford decided to clearly differentiate their professional duty pickup trucks called the Super Duty. Featuring a distant exterior appearance from the F-150 as well differential mechanical equipment, the entry-level model to the 1999 Ford Super Duty line was the F-250. Available in regular cab, extended Supercab and Crew Cab configurations, the 1999 Ford Super Duty F-250 received standard engine power, a 255-horsepower 5.4-liter V-8 powerplant. A ten-cylinder 6.8-liter engine and a 7.3-liter Power Stroke turbocharged diesel producing 525 lb-ft of torque was optional on the Ford Super Duty F-250. In 2003, a more powerful 6.0-liter Power Stroke diesel replaced the larger displacement unit.
Automatic and manual transmission choices were offered on the Super Duty F-250 including a six-speed manual featuring integrated power take-off. The Ford Super Duty F-250 was available with two-wheel and four-wheel drivetrains. In years following the Ford Super Duty F-250’s launch, the truck began to boast added trim levels such as the XLT, Lariat, King Ranch and a Harley-Davidson edition in 2004. Restyled with a taller front grille, revised interior and new headlamps in 2005, the Ford Super Duty F-250 was also granted greater payload as well as enlarged disc brakes. Performance from the Ford Super Duty F-250’s gasoline engines was also improved for 2005. A completely new Ford Super Duty F-250 was introduced for 2008.